Homemade Safer’s End All Spray Miticide: An Effective Soft-Bodied Pest Miticide You Make At Home

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  • Post last modified:June 30, 2025
  • Post category:Gardening

This homemade miticide spray combines neem oil, insecticidal soap, isopropyl alcohol, adhesion oil, and is lightly scented for use on indoor tropical plants.

Homemade Safer's End All miticide spray

It mimics Safer’s brand End All spray which is half of my two-part integrated pest management regimen for my apartment-based tropical collection.

I like to bulk purchase products I’m using on a regular basis, month after month, so rather than buying endless bottles of Safer’s End All – which is a very effective product to combat Thrips, Mites, Fungus Gnats and Aphids – I’ve created a homemade version of their popular miticide spray that uses the same active ingredients at roughly the same strengths.

It’s safe for indoor use when applied at lights-off, and I use it every 30 days as a preventative measure, then if I see a light infestation break out, I bump that area to every 5–7 days to break the life cycle.

This DIY Spray Is Effective Against Thrips, Mites, Fungus Gnats and Aphids

This DIY all-in-one pest control concentrate mimics Safer’s End All using neem oil, insecticidal soap, and isopropyl alcohol.

It’s designed for indoor tropical collections and is effective against a wide range of soft-bodied pests when used monthly or during early infestations.

Pest TypeEffectivenessNotes
ThripsGoodKills larvae and adults on contact; rotate with Spinosad for best control
Spider MitesGoodKills nymphs and adults; does not affect eggs
Fungus GnatsModerateHelps reduce adults and surface larvae when sprayed into soil
AphidsGoodVery effective on soft-bodied clusters
MealybugsModerateWorks on nymphs; may require repeat applications
WhitefliesMildSuppresses small populations if sprayed directly

Homemade Miticide Spray Formula For Soft-Bodied Pests

  • Makes 1L of concentrate
  • Store concentrate for up to 3 months in cool, dark place
  • A very effective spray when dealing with infestations of Thrips, Mites, Fungus Gnats and/or Aphids.

Miticide Ingredients

IngredientAmount (grams)Purpose
Insecticidal soap (liquid)400 gMain pest-killing agent
Cold-pressed neem oil (100%)250 gKills + repels pests, mild fungicide
Isopropyl alcohol (70%)150 gEnhances mite/thrip knockdown
Sunflower or canola oil50 gHelps adhesion, mimics spreaders
Essential oil1–2 g (~20–40 drops)Scent + mild deterrent. To your liking. Suggestions: peppermint/lavender/lemongrass
Water (filtered, warm)Top up to 1000 gHelps emulsify + adjust texture

Mixing Procedure For 1 Litre of Miticide Concentrate

  1. Combine warm water + soap first (stir gently).
  2. Add neem oil + sunflower oil; stir until emulsified.
  3. Add isopropyl alcohol.
  4. Add essential oils last. Stir again.
  5. Store in a dark, cool bottle. Shake well before each use.


Mixing The Miticide For Spray Application

  • Scale up your mix by maintaining a 1:16 ratio (ie. 1 part concentrate, 16 parts water)

Mixing for Spray Application (500 mL Spray Bottle)

For a 500mL spray bottle, I use the following formula:

Measurement ToolAmount of ConcentrateTop Up With Water
Tablespoon2 Tbsp (30 mL)To 500 mL
Teaspoon4 tsp (20 mL)To 500 mL
Ratio~1 part concentrate : 16 parts water

Mixing for Spray Application (750 mL Spray Bottle)

Measurement ToolAmount of ConcentrateApprox. Weight (g)Top Up With Water
Tablespoon3 Tbsp (45 mL)~45 gTo 750 mL
Teaspoon9 tsp (45 mL)~45 gTo 750 mL
Ratio~1 part concentrate : 16 parts water

Mixing for Spray Application (1 L Spray Bottle)

Measurement ToolAmount of ConcentrateApprox. Weight (g)Top Up With Water
Tablespoon4 Tbsp (60 mL)~60 gTo 1 L
Teaspoon12 tsp (60 mL)~60 gTo 1 L
Ratio~1 part concentrate : 16 parts water

How to Use This Highly Effective Homemade Miticide In Your Garden

  • Apply every 30 days for prevention, as part of an integrated pest management regimen.
  • Use every 5–7 days whenever you see an outbreak or mild infestation, the important part is to break the pest’s life cycle.
  • Spray at dusk/lights off. Avoid spraying in direct sun or under grow lights.
  • Mix just before use. Shake the concentrate well before pouring.
  • Test on a small area first (especially velvety leaves), or consider starting with a bottle of Safer’s End All to see if you even like this as a pest management miticide spray.

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